Multiple studies have estimated millions will die annually as a result of the Trump Administration’s closure of the foreign-aid agency.

The analysis, published in the Lancet, estimates the agency’s programs saved 91 million lives worldwide over two decades, playing a vital role in global health.

Steep cuts to the US Agency for International Development threaten to cause more than 14mn extra deaths by 2030 and reverse some gains made against diseases such as HIV/Aids, malaria and respiratory infections, new research has warned.