Background Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that affects medium-sized arteries with multifocal (beaded) or focal stenotic lesions, aneurysms, dissections and ...

Objective Early intervention for asymptomatic severe aortic stenosis (AS) has shown prognostic benefits; however, some ...

Background Antiretroviral therapy (ART)-treated people with HIV (PWH) have increased risk of heart failure with preserved ...

Background Percutaneous patent foramen ovale (PFO) closure is an established intervention for secondary prevention of ...

Background Up to 30% of patients undergoing transcatheter aortic valve implantation (TAVI) have presented to hospital with ...

Background and objectives The History, ECG, Age, Risk factors and Troponin (HEART) score is widely used for emergency ...

Background Observational studies have reported that sleep is associated with the risk of major depressive disorder (MDD) and cardiovascular diseases (CVDs). However, the causal relationships among ...

Objective We investigated the benefit of Impella, a modern percutaneous mechanical support (pMCS) device, versus former standard intra-aortic balloon pump (IABP) in acute myocardial infarction ...

Cardiovascular disease is the leading cause of premature mortality in the developed world, and hypertension is its most important risk factor. Controlling hypertension is a major focus of public ...

Background Many district general hospitals (DGHs) in the UK do not have resident on-call cardiology registrars overnight; in these situations, it is becoming more common for cardiac outreach ...

Background Amyloid transthyretin (ATTR) amyloidosis is a rare, life-threatening disease frequently manifesting with cardiomyopathy (ATTR-CM), polyneuropathy (ATTR-PN) or both (ATTR-mixed). We ...

Background Ranolazine is an antianginal drug reported to have hypoglycaemic effects. Objectives To assess the effect of ranolazine versus placebo on glycaemic control for adults with and without ...