The SMU Mustangs and the Louisville Cardinals meet Saturday in Louisville, Kentucky. Kickoff is slated for 3:30 p.m. ET.

A second cow on the same southwest Livingston County farm has tested positive for rabies. Here's what to know.

Two people who later tested positive for measles traveled through Frederick Douglass Greater Rochester International Airport ...

Livingston County health officials are warning people and animals to stay out of areas where blooms are present. The public ...

New York reported 22 more confirmed cases in its latest weekly update. Here's the latest statewide total and what to know about the illness.

Two drivers were seriously injured Thursday morning when their vehicles collided head-on in Caroline, southeast of Ithaca. One man was flown to Strong Memorial Hospital in Rochester, State Police said ...

Sal Maiorana and Adam Benigni break down Thursday night's Highmark Stadium opener as the Bills rolled the Lions.

The Bills rolled past the Lions 41-31 in the debut game at Highmark Stadium. Here are Sal Maiorana's main takeaways.

OneRepublic will play a 3-4 song halftime show during Bills vs. Lions. Prime Video will show part of the concert.

The voice of Moana is singing the national anthem before Bills vs. Lions. Here's what to know about Auliʻi Cravalho.

The Bills moved across the street to a new $2.2 billion stadium. Their 53-year-old former home is being demolished piece by ...

The Strong celebrates Hispanic Heritage Month Sept. 19 with bachata, food, book readings, crafts and other family activities.