Researchers at Peking University has developed a "two-step" signaling switch—transitioning from Hippo-YAP/Notch to TGFβ1 ...

We conducted coculture experiments to analyze trophoblast RARRES2 and macrophage CMKLR1 interactions, performed luciferase and chromatin immunoprecipitation assays to validate transcription factors ...

Phase II Trial of TAS-102 in Colorectal Cancer Patients With Circulating Tumor DNA-Defined Minimal Residual Disease After Adjuvant Therapy: INTERCEPT-TT A multiplex QIF assay was optimized on tissue ...

Preeclampsia, a severe pregnancy complication with an incompletely deciphered cause, is strongly associated with hyperlipidemia. Our previous studies demonstrated that FTL (ferritin light chain) ...

The placenta, a key organ connecting the mother and fetus, plays a vital role in gas and nutrient exchange and growth factor and hormone secretion. The crucial functions of the placenta are largely ...

Conventional human pluripotent stem cells at the primed pluripotent state are capable of generating all the embryonic lineages. However, their extraembryonic trophectoderm potentials is limited. It ...

PHILADELPHIA--(BUSINESS WIRE)--#acceleratedbio--Accelerated Biosciences and Stemmatters are thrilled to announce their strategic partnership aimed at co-developing and co-marketing human induced ...

PHILADELPHIA--(BUSINESS WIRE)--Accelerated Biosciences and Stemmatters are thrilled to announce their strategic partnership aimed at co-developing and co-marketing human induced pluripotent stem cells ...

Although GTD starts in the womb, it behaves very differently from cancer of the womb. It is also treated differently. If you are looking for information about womb cancer go to our womb cancer section ...

Dose escalation and expansion results from the phase I study of F0024, a trophoblast cell-surface antigen 2 (TROP2) antibody-drug conjugate (ADC), in patients (pts) with advanced solid tumors. This is ...

In the human placenta, there are placental villi, and the surface of the villi consists of syncytiotrophoblast, also called barrier cells, that serve as the main barrier against foreign substances.

Researchers have created a stem cell-based organoid model of the placental barrier, offering a new tool for studying placental function and drug toxicity, potentially improving fetal safety in drug ...