Gallstone disease is common, but its genetic basis remains incompletely understood. Here, the authors conduct a trans‑ancestry GWAS identifying 116 risk loci, linking gallstone susceptibility to lipid ...
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Scientists identify rare mutations in 36 genes that sharply raise the odds of OCD and tic disorders
A large-scale genetic analysis has identified 36 genes carrying rare mutations that substantially increase the likelihood of developing obsessive-compulsive disorder, chronic tic disorders, or both.
An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...
Former biologics boss Peter Marks had a vision. With the FDA’s latest draft guidance, it’s coming to fruition. Speaking with BioSpace, current CBER leader Karim Mikhail said the “adapted pathway” is ...
Mutations found in roughly 20% of human cancers may promote tumor growth by changing how DNA is organized inside cells.
Scientists at the Icahn School of Medicine at Mount Sinai have developed a novel artificial intelligence tool that not only identifies disease-causing genetic mutations but also predicts the type of ...
This voice experience is generated by AI. Learn more. This voice experience is generated by AI. Learn more. A rare, inherited mutation can significantly increase the chances of developing lung cancer, ...
A man sits outside and holds a slim menthol cigarette between his fingers. Close-up with focus on the cigarette. The study provided a comprehensive examination of how lifestyle and environmental ...
People who have never smoked may still be at a much higher risk of developing lung cancer if they have a certain rare genetic mutation. That’s according to a new study, which suggests that carriers of ...
A missense mutation in the sheep MC4R gene, enriched in year-round estrus breeds, boosted receptor signaling and ...
Behavioural genetics is the interdisciplinary effort to establish causal links between genes and animal (including human) behavioural traits and neural mechanisms. Methods used include twin studies, ...
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