Though neither a physiologist nor a physician, William Shakespeare, a master observer, deftly noted the central roles of the ...

Despite notable advancements in the acute and long-term management, coronary artery disease and myocardial infarction (MI) remain the leading cause of mortality worldwide. Atherothrombosis overlying ...

BACKGROUND: Evidence of the diverse genetic architecture of dilated cardiomyopathy (DCM) continues to emerge and requires ...

My experiences reflect knowing a community from the inside rather than judging it from the outside. Detroit was often depicted as lacking promise, but those within it recognized strengths that made ...

BACKGROUND: Cardiac troponin is increasingly used for cardiovascular risk prediction. While abnormal values often reflect subclinical cardiovascular disease, they can be raised due to interference, ...

All living organisms on Earth demonstrate rhythms in biological function, which are approximately tied to the 24-hour cycle of a single day and night. The term diurnal is commonly used to describe ...

Dysphagia is common after stroke and associated with a poor outcome. Swallowing therapies for dysphagia are aimed at accelerating recovery of swallowing. This is an update of a 2012 Cochrane review ...

Most composite end points for trials of a drug or device use a time-to-event or repeated-events approach for 2 clinically relevant outcomes (ie, death or hospitalization) that are assessed over the ...

Most physicians in the 1920s were general practitioners with relatively little postgraduate training. Although they measured blood pressure routinely, electrocardiograms and chest X-rays were in the ...

In 2017, the American Academy of Pediatrics issued a new clinical practice guideline for defining hypertension in children as an update to the previous Fourth Report guidelines issued in 2004.

The range of clinical responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is extremely broad. Although most patients with coronavirus disease 2019 (COVID-19) present ...

In summary, our study demonstrated that exercise protects DiaCM, at least in part, through NAT10-mediated enhancement of ac4C modifications on key ferroptosis regulators and the subsequent reduction ...