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In his first game against his former team, McCaffrey had 142 scrimmage yards and a touchdown as the 49ers won 20-9.

In the second half, Purdy and Co. settled down, extending their lead with an 80-yard touchdown drive in the early stages of ...

Catch Bryce Young and the Panthers (6-5) against Brock Purdy and the 49ers (7-4) at 8:15 p.m. ET on ESPN with streaming ...

However, Ruben Amorim’s first anniversary of his maiden game in charge of the club, ended in defeat as Kiernan ...

Find out why Xavier Legette anchors our all-wide receiver same-game parlay play for MNF. Free Panthers vs. 49ers SGP picks ...

With a win tonight, the 49ers’ odds of making the playoffs move from 83 percent from 89 percent in The Athletic’s NFL Playoff ...

Mike McClure and Alex Selesnick share their anytime touchdown props for Monday Night Football ...

The Carolina Panthers and the San Francisco 49ers take the field for NFL Monday Night Football tonight in Week 12. MNF start ...

The Carolina Panthers face the San Francisco 49ers on Monday, Nov. 24, 2025 at Levi’s Stadium in Santa Clara, California.

The San Francisco 49ers (7-4) host the Carolina Panthers (6-5) on Monday Night Football in a key battle for NFC playoff ...

The Panthers hit the road to take on the 49ers on Monday Night Football. The 49ers/Panthers game starts at 8:15 p.m. ET on ...