No. 17 USC recorded a statement win with a 26-21 victory over No. 21 Iowa at home. The Trojans held the Hawkeyes scoreless in the second half and erased an early 21-7 deficit to move to 8-2 (6-1 Big Ten). USC was powered by another big performance from star wide receiver Makai Lemon, who finished with 10 catches for 153 yards and a touchdown.

The stakes are higher with a loaded slate of huge games. Here's the full Week 12 college football schedule with links to all the game previews and predictions.

Kenyon Sadiq is among the standout tight ends in college football, and we expect the Ducks star to remain a go-to force inside the red zone on Saturday.

The model simulates every FBS game 10,000 times. Since its inception, it has generated a betting profit of over $2,000 for $100 players on its top-rated college spread football picks. Anybody following its college football betting picks at sportsbooks and on betting sites could have seen strong returns.

Our Week 12 ATS college football picks are taking the points with Texas against Georgia and backing Alabama against Oklahoma at home.

Let's take a look at the best games to watch this weekend, with odds via DraftKings Sportsbook as of Nov. 13. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

It's Florida vs Ole Miss in Week 12 of the 2025 college football season. Who wins? See our predictions and picks, plus the odds for the game.

There were a handful of notable takeaways from Week 12 of the college football season, but none bigger than Oklahoma knocking off Alabama in Tuscaloosa, shaking up the College Football Playoff picture in the process.

The UCLA Bruins and Ohio State Buckeyes play on Saturday, Nov. 15, at Ohio Stadium in Columbus, Ohio, in a game on the college football Week 12 schedule. Which team will win the college football Week 12 game? Check out these college football Week 12 picks ...

Thomas Casale has locked in his top three college football picks for Week 12 and his CFB parlay could pay out nearly +600