Though neither a physiologist nor a physician, William Shakespeare, a master observer, deftly noted the central roles of the ...

Despite notable advancements in the acute and long-term management, coronary artery disease and myocardial infarction (MI) ...

BACKGROUND: Evidence of the diverse genetic architecture of dilated cardiomyopathy (DCM) continues to emerge and requires ...

My experiences reflect knowing a community from the inside rather than judging it from the outside. Detroit was often depicted as lacking promise, but those within it recognized strengths that made ...

BACKGROUND: Cardiac troponin is increasingly used for cardiovascular risk prediction. While abnormal values often reflect ...

The 2026 Statistics Update uses language that conveys respect and specificity when referencing race and ethnicity. Instead of referring to groups very broadly with collective nouns (eg, Blacks, Whites ...

eLetters should relate to an article recently published in the journal and are not a forum for providing unpublished data. Comments are reviewed for appropriate use of tone and language. Comments are ...

Background: Heart failure (HF) is a complicated syndrome where ~50% of patients die within 5 years of diagnosis. Years of life lost (YLL) is a population-based mortality indicator that takes into ...

A 23-year-old man admitted to an intensive care unit with Staphylococcus bacteremia presented with soft heart sounds and a to-and-fro murmur, which progressed to a silent precordium within 24 hours.

Branded medications dominated the prescription market in the 1980s, constituting 81% of fills in the United States. A majority lacked generic equivalents even after patent expiry. In 1984, the ...

Platypnea-orthodeoxia is a relatively uncommon but striking clinical syndrome characterized by dyspnea and deoxygenation accompanying a change to a sitting or standing from a recumbent position. Since ...

The heart is a pump, supplying hydraulic energy to maintain the circulation. The rate of energy output is termed cardiac power output (CPO). The subanalysis of the SHOCK trial (Should We Emergently ...