Can the Rams and Chargers bounce back from dispiriting openers? Will Baker Mayfield get his revenge? Week 2 has some fun matchups.

Later, the Denver Broncos will also look to avoid falling to 0-2 when they host the Jacksonville Jaguars in a battle between two of last season's top AFC teams. The Seattle Seahawks, meanwhile, will seek to improve to 2-0 without their starting quarterback as they take on the Arizona Cardinals.

NFL after Week 2, who are the MVP candidates and the over/under options, plus what teams look like Super Bowl contenders already and who looks done

Week 2 of the NFL season saw Marcus Mariota take over as the Washington Commanders’ starting quarterback, Denver quarterback Bo Nix bounce back from a subpar Week 1 performance, Los Angeles Chargers quarterback Justin Herbert struggle again,

Grading all 16 NFC teams after Week 2 in the NFL.

It's the Colts vs Chiefs tonight on NBC and Peacock. Live coverage begins at 7 PM ET.

Below, we've rolled out five best bets for Week 2, as well as hand out a pick for every other matchup that'll take place on Sunday (and Monday) for you to either fade or follow. Let's not waste any more of your valuable time and get right into the picks! NFL odds courtesy of DraftKings Sportsbook.

The second week of the NFL season proved to be a brutal one for three young quarterbacks who were expected to take major leaps this season.