Los Angeles Rams All-Pro edge rusher Myles Garrett and New England Patriots Pro Bowl wide receiver A.J. Brown -- are sidelined for multiple weeks and plenty of other high-impact contributors were injured on Sunday.

Los Angeles Rams' Myles Garrett was struggling before the season started.

The Los Angeles Rams entered the 2026 NFL season as the Super Bowl favorites, and they quickly disappointed on Thursday Night Football against the San Francisco 49ers. While the game was played in Melbourne,

Byron Young will become the Rams' top edge rusher with Myles Garrett out, giving him his biggest opportunity yet in a contract year.

Myles Garrett was traded from the Browns to the Rams during the 2026 NFL offseason. Here's the full details of how the blockbuster came together.

The Los Angeles Rams made a blockbuster trade for Myles Garrett this offseason, hoping the defensive end would give them an elite defensive line.

The Los Angeles Rams do not have a timeline for Myles Garrett's potential return after he undergoes knee surgery, coach Sean McVay said Monday.

Myles Garrett recorded zero tackles and zero sacks in his Rams debut, citing a lingering knee injury during the season-opening loss to the 49ers.

“This was the worst version of myself that I’ve put out there,” Garrett said. “I’ve got to be better. I’ve got to find a way to recover and get back to the player I know I can be and I’ve shown that I’ve been before.”