Karolinska Institutet reports ROR1 inhibitor KAN571C wipes out double‑resistant MCL after ibrutinib/venetoclax, spotlighting a promising target. A small molecule inhibitor of ROR1, a receptor largely absent from normal adult tissue but overexpressed in mantle cell lymphoma (MCL),

Dart was cut down early in the Giants' loss to the Rams on Monday night. He appears to have avoided serious injury, although he is expected to miss multiple games as a result of his malady.

Jaxson Dart was supposed to lead the New York Giants back to relevance for the first time since the days of Eli Manning in his first full season as a starter.

Kyle Shanahan said Jake Tonges will undergo season-ending surgery to repair his torn MCL. Tonges went down with the injury in Week 1. He filled in for George Kittle admirably last year and was likely going to play a role in the offense for the first month of this season as Kittle got up to full speed.

Saints RB Alvin Kamara has "no limitations," was a full participant in practice and said his knee feels good just one month after spraining his MCL in practice.

Projecting the outlook for some of the league's biggest Week 2 injuries

49ers tight end Jake Tonges's final play of the 2026 season was a painful one in more ways than one.