The Arizona Cardinals and head coach Mike LaFleur are now back to the drawing board. The Cardinals‘ ugly 31-7 loss to the Seattle Seahawks on Sunday afternoon is a culmination of a poor second half showing.

In the Arizona Cardinals ' 31-7 loss to the Seattle Seahawks, 18 players participated in at least one of the 50 offensive snaps. Prior to the final two plays, the offense managed 20 yards in the final two quarters on 12 plays.

Check out all the ways to watch, listen and live stream the Arizona Cardinals against the San Francisco 49ers on September 27, 2026

San Francisco 49ers vs Arizona Cardinals odds for NFL Week 3 game betting, including point spread, moneyline, over/under for Sunday, Sept. 27, 2026.

What channel is Arizona Cardinals vs San Francisco 49ers on? How to watch, how to stream NFL Week 3 game on TV, streaming on Sunday, Sept. 27, 2026.

Jaxson Dart may miss a long time for knee injury, surgery, and recovery. The New York Giants need a stopgap solution. They cannot depend solely on Jameis Winston. Arizona Cardinals quarterback Gardner Minshew II could be a viable option.

The Arizona Cardinals are set to face the Seattle Seahawks. You've got questions. I've got answers.

Cardinals fans reacted to a tough loss against the Seattle Seahawks at State Farm Stadium, with some expressing excitement for a new coach alongside frustration at the home opener.