HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...

Researchers at The University of Texas MD Anderson Cancer Center have developed a new computational approach designed to ...

Northwestern Medicine scientists have discovered a potent immunotherapy approach for treating meningiomas, the most common ...

The so-called guards are tumor macrophages. Under normal conditions, macrophages serve as first responders, helping fight infections and repair tissue damage. Inside tumors, however, these cells are ...

Combined epigenetic and immune checkpoint therapy altered the tumour microenvironment in platinum-resistant ovarian cancer.

The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...

A gene expression program executed by neutrophils and a corresponding biomarker support tumor progression across human and murine tumors.

Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer. Published in the scientific journal ...

In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy ...