Researchers identify tanycytes as a critical mechanism for clearing toxic tau protein from the brain, offering a new target ...

Alzheimer's-related brain changes progressed up to 20 times faster in women who also had abnormal levels of a ...

Summary: Women make up nearly two-thirds of Alzheimer’s patients, and researcher may have just discovered a massive reason why. A new study found that when the protein alpha-synuclein (typically ...

A review published in Genomic Psychiatry by Dr. Peng Lei and colleagues presents a sweeping synthesis of tau protein research that fundamentally reframes our understanding of this molecule's dual ...

Scientists at the University of Kentucky have uncovered a new reason why people with Alzheimer's disease often struggle with sleep, long before memory loss begins. The study, led by researchers at the ...

Researchers at UCLA Health and UC San Francisco have identified a specific molecular mechanism that explains why certain ...

Scientists are exploring many ways to tackle tau pathology. In the October 17 Cell Chemical Biology, researchers led by Jian-Zhi Wang at the Huazhong University of Science and Technology, Wuhan, China ...

By Tarun Sai Lomte Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau regulation and future diagnostic strategies Study: ...

Blood levels of total-tau — a protein signalling axonal damage in the brain — could be used as a biomarker to gauge severity of concussions in athletes and to assess when it is safe to return to play, ...

A mechanistic summary of anti-tau therapeutic strategies. Reduction of tau expression. The use of antisense oligonucleotides (ASOs) and small molecules can reduce tau production. CHENGDU, Sichuan, ...