Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune ...

In today’s rapidly evolving scientific landscape, eliminating barriers to progress is more critical than ever. Precision medicine and targeted therapies hold great promise but are dependent on the ...

Immune cells (NK and cytotoxic T cells) are activated by short-synthetic mRNA which binds to the ZC3H12D receptor and is transported to the nucleus where it induces the expression of GZMB, a key ...

Biochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Researchers have discovered that misreading of ...

The approval of messenger RNA (mRNA) based COVID-19 vaccines marked a pivotal scientific milestone, establishing mRNA as an innovative drug modality with immense therapeutic potential. However, due to ...

SAN DIEGO, Feb. 16, 2023 (GLOBE NEWSWIRE) -- Telesis Bio Inc. (NASDAQ: TBIO), a leader in automated multi-omic and synthetic biology solutions, today announced the availability of its BioXp® Select ...

Image of the mRNA technology used in COVID-19 vaccines. The researchers discovered that these mRNA-carrying lipid nanoparticles could overcome challenges associated with conventional stem cell ...

Editorial: Over the holiday period, the Guardian leader column is looking ahead at the themes of 2026. Today we examine how the White House’s war on vaccines has left the future of a key technology un ...

Monday morning’s news that Drs. Katalin Karikó and Drew Weissman were awarded the Nobel Prize in Physiology or Medicine has cast a spotlight on their seminal work leading to the development of the ...

Researchers have discovered that misreading of therapeutic mRNAs by the cell's decoding machinery can cause an unintended immune response in the body. They have identified the sequence within the mRNA ...