BUFFALO, N.Y. — Remyelination, the spontaneous regeneration of the fatty insulator in the brain that keeps neurons communicating, has long been seen as crucial to the next big advance in treating ...

People with multiple sclerosis exhibit variable degrees of remyelination. Individuals with greater capacity to remyelinate seem to have less clinical disability, thereby fuelling the research to find ...

As described in the journal Cell Reports, the team found that in adult stem cells, the activation of a specific transcription factor induces pathological quiescence – where the stem cells become ...

CNS remyelination is the regenerative process by which myelin sheaths are restored to demyelinated axons. Unlike the poor regeneration that occurs following neuronal injury, remyelination can occur as ...

Ari Green, MD, of the University of California, San Francisco, details the benefits of remyelination for patients with multiple sclerosis (MS), as well as the challenges faced when conducting ...

Researchers have revealed the molecular mechanism involved in the process of repair to damage of the myelin sheath.This achievement shows that it is possible to encourage the regeneration of the ...

Please provide your email address to receive an email when new articles are posted on . Nearly all patients in the open-label extension of VISIONARY-MS showed MRI evidence of neuronal repair and ...

BUFFALO, N.Y. — New research on remyelination, the spontaneous regeneration of the brain’s fatty insulator that keeps neurons communicating, could lead to a novel approach to developing treatments for ...

Remyelination would be crucial, therefore, in interrupting this disease pathology. Not all patients with MS would respond to attempts at remyelination . Once the disease becomes chronic , ...

Long term extension of the Phase 2 VISIONARY-MS clinical trial of CNM-Au8 demonstrated significant evidence of repair and remyelination across multiple paraclinical endpoints (change from original ...

A recent study analyzed the role of purinergic receptor P2X4 in microglia/macrophages during autoimmune inflammation, finding that P2X4 receptors modulate microglia/macrophage inflammatory responses ...

SALT LAKE CITY, April 08, 2025 (GLOBE NEWSWIRE) -- Clene, Inc. (Nasdaq: CLNN) and its subsidiary, Clene Nanomedicine, Inc., a clinical-stage biopharmaceutical company dedicated to advancing therapies ...