How can molecular structures be analysed when the resolution of the techniques available is not sufficient? Researchers from the fields of physics, chemistry and medicine at Heinrich Heine University ...
Since its discovery in the 1990s, "programmed cell death protein 1," or PD-1, has been regarded as a leading target in cancer treatments. A "checkpoint" receptor that often resides on the surface of ...
Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their ...
Scientists are making waves with a novel therapy for metastatic colorectal cancer (mCRC) that combines two powerful antibodies—one targeting epidermal growth factor receptor (EGFR), the other ...
The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...
Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...
The programmed death receptor-1-blocking antibody is approved as a single agent or in combination with chemotherapy. (HealthDay News) — The U.S. Food and Drug Administration has approved the humanized ...
China Pharmaceutical University has patented non-ubiquitin proteolysis targeting chimera (NuTACs) comprising proteasomal ubiquitin receptor ADRM1 (ARM1; hRpn13) linked to programmed cell death 1 ...
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