A lineage-tracing study in mice shows that oocytes activated early in life can persist for nearly the entire reproductive ...

Oocyte in vitro maturation is a technique in assisted reproductive technology. Thousands of genes show abnormally high expression in in vitro maturated metaphase II (MII) oocytes compared to those ...

Oocyte/zygote/embryo maturation arrest (OZEMA) causes recurrent failure of oocyte maturation, fertilization, or early embryonic development, but its genetic basis and ...

Primordial germ cells, which emerge around day 16 in early human embryos, develop to form oogonia so that eventually, the number of oocytes that are present in an adult female is fixed at birth. After ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...

The genome—which contains genes encoded in DNA—acts as the fundamental blueprint of life. But what you might not know is that, in addition to this genetic information, we have something akin to an ...

A team of reproductive biologists at Nanjing Agricultural University has found that spermidine, a polyamine metabolite, helps oocytes clear away damaged mitochondria in mice, thereby improving ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

Researchers led by Kyushu University have succeeded in using mouse stem cells to reconstruct structures in the ovarian environment critical for the generation of mature egg cells. Moreover, they were ...

Age, ovarian reserve, prior surgery, and disease severity influence fertility preservation decisions, making individualized ...

The accumulation of misfolded or damaged proteins in long-lived, non-dividing cells like neurons are linked to neurodegenerative diseases like Alzheimer's. A study now finds that the build-up of these ...