Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...

This work not only identified the genetic cause of RP but also further highlights the role that noncoding genes can have in genetic disorders.

Researchers from Radboud University Medical Center and University of Basel have discovered new genetic causes of inherited ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in ...

The puzzle seems impossible: take a three-billion-letter code and predict what happens if you swap a single letter. The code we’re talking about—the human genome—stores most of its instructions in ...

Researchers at the Icahn School of Medicine at Mount Sinai, and collaborators at the University of Bristol, KU Leuven, and the NIHR BioResource, have identified a neurodevelopmental disorder, caused ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. UCLA researchers, using an experiment that elucidated the function of tens of thousands of ...

A new multi-omics approach to unpicking how noncoding gene variants influence the development of common chronic diseases has identified tens of thousands of instances where variants have an impact on ...

Researchers disagree on the number of genes in the human genome, in part because what exactly a gene is can be difficult to determine. At the turn of the century, while awaiting the completion of the ...