MHC class II molecules are central to the adaptive immune response, serving as the means by which antigen-presenting cells, notably dendritic cells, display processed peptides to CD4+ T cells. This ...
Major histocompatibility complex class II (MHC-II) molecules play a critical, yet historically overlooked, role in tumor immunity. This review synthesizes emerging mechanistic evidence showing that ...
In a recent article posted to the bioRxiv* preprint server, researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
Cabozantinib As Salvage Therapy for Patients With Tyrosine Kinase Inhibitor–Refractory Differentiated Thyroid Cancer: Results of a Multicenter Phase II International Thyroid Oncology Group Trial ...
A study published in the journal Nature, led by Carlene Zindl, Ph.D., and C. Garrett Wilson in the research group of Casey Weaver, M.D., at the University of Alabama at Birmingham, brings new ...
ROS are key players in the immune system's response to infection and cancer, influencing how the body identifies and fights these threats. A balanced level of ROS supports healthy immune function, but ...
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