A molecule designed to activate iron locked up in organelles called lysosomes and thereby induce cell death might offer a way to tackle treatment-resistant cancer. Building on the foundation provided ...

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes. Once alerted, the body's ...

The body has to clear away dead cells and other unnecessary or unneeded stuff, and one mechanism that is crucial to the degradation of such materials is called LC3-associated phagocytosis (LAP). This ...

Researchers have discovered a unique type of fat molecule in the brain may have anti-inflammatory effects and play a crucial role in preventing age-related neurological disease. Animal studies ...

In experiments using neonatal mice, researchers have identified a fatty molecule in breast milk that triggers a process in which stem cells in the brain produce cells that create new white matter, ...

Our understanding of how cells recycle lipids through autophagy -- a form of cellular degradation -- has grown significantly, thanks to a recent study. Using yeast as a model organism, the researchers ...

UCLA researchers have found that the metabolism of certain lipids is linked to chronic inflammation in the intestines. The study identified a specific type of lipid – very long chain ceramide – as ...

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid ...

Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid. This lipid ...

Omega-3 fatty acids could help to protect women against Alzheimer's—with women "disproportionately impacted" by the disease compared to men. It seems there is a noticeable loss of unsaturated fats, ...

A University of the Basque Country (UPV/EHU) study proves that the WIN55.212-2 drug protects the brain and reverses the initial cognitive damage caused by dementia. The UPV/EHU's Neurochemistry and ...