Technology Networks

Two-Step Herpes Vaccine Combines IM Shot with Vaginal Nanoparticle Delivery

A nanoparticle-based “prime and pull” vaccine strategy resulted in strong immune responses in vaginal tissue. In preclinical ...
Nature

Safety and Immunogenicity of aerosolized adenovirus-vectored COVID-19 vaccine and intramuscular mRNA vaccine bivalent boosters: a randomized open-label clinical trial

Both SARS-CoV-2 mRNA and mucosal vaccines induce protective immunity against COVID-19 but showed different immune profiles. We conducted a longitudinal head-to-head analysis of the safety and ...
Nature

Effects of cellular receptors on the vaccine efficacies of adenovirus vector-based vaccines following intramuscular and intranasal administration

The global outbreak of the novel coronavirus disease (COVID-19) has emphasized the critical importance of vaccines in combating infectious diseases worldwide. In particular, the unprecedented speed of ...

Prime-and-pull vaccine may offer lasting genital herpes protection

Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or ...
News-Medical.Net

Prime and pull vaccine approach prevents genital herpes infection

Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or ...