Researchers at The Institute of Cancer Research, London identified the CIP2A–TOPBP1 complex as a master regulator of DNA repair during mitosis, coordinating backup pathways that protect chromosomes ...
Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...
ETX-19477 is a potent, selective inhibitor of poly (ADP-ribose) glycohydrolase (PARG), an enzyme that plays a role in the DNA ...
Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this ...
This transcript has been edited for clarity. For more episodes, download the Medscape app or subscribe to the podcast on Apple Podcasts, Spotify, or your preferred podcast provider. Dr Liu is a ...
Understanding why cancer cells rely on specific genes is critical for designing effective targeted therapies. A new study ...
ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.
A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...
A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...