Traditional descriptions of the cortical cholinergic input system focused on the diffuse organization of cholinergic projections and the hypothesis that slowly changing levels of extracellular ...

Acquisition of drug-reinforced behavior is accompanied by a systematic increase of release of the neurotransmitter acetylcholine (ACh) rather than dopamine, the expected prime reward neurotransmitter ...

A line of genetically modified mice that scientists call "Forrest Gump" because, like the movie character, they can run far but they aren't smart, is furthering the understanding of a key ...

Karolinska Institutet researchers identified dopamine-acetylcholine disruptions in the basal ganglia as key contributors to autism-related behavioral inflexibility. Using advanced techniques like ...

Acetylcholine plays a vital role as a neurotransmitter that oversees cognitive tasks, memory, and the regulation of mood. With aging, our body’s generation of acetylcholine decreases, which could ...

Two new reports this week show what can happen when neurotransmitters get out of whack, with ramifications for Alzheimer disease and Parkinson disease. First, a paper in the September 7 Neuron ...

A recent study published in Neuron on March 19, 2025, explores how the interaction between dopamine and acetylcholine in the brain influences sexual behavior in male mice. This research sheds light on ...