A shelter-in-place has been issued after a UPS plane crashed near the Louisville International Airport in Kentucky, officials said.

Nine people remain missing after a UPS plane departing Louisville Muhammad Ali International Airport in Kentucky on Tuesday crashed, killing at least 12 people.

The ashes have settled over the charred Louisville neighborhood where nine people remain missing and families cling to hope as investigators comb through the wreckage of Tuesday’s fatal UPS cargo plane crash.

There was a fire in the UPS plane's left wing and the engine "detached" during takeoff from Louisville International Airport in Kentucky, the NTSB official said.

Former colleagues are mourning three pilots killed in the UPS cargo plane crash near the Louisville, Kentucky, airport, as relatives of a badly burned man who was pulled from the wreckage confirm he’s also among the 14 who died.

The crash near Louisville Muhammad Ali International Airport marked the deadliest accident in UPS Airlines history. Here's what we know now.

The NTSB is charged with finding out the probable cause for why UPS Flight 2976 crashed in Louisville. Here's what to know about the investigation.

UPS has grounded its fleet of McDonnell Douglas MD-11s, the type of plane involved in Tuesday’s deadly crash in Louisville, Kentucky, the company confirmed Friday. Now, the FAA is ordering an investigation into those planes before they can fly again.

LOUISVILLE, Ky. (AP) — Videos from phones, cars and security cameras captured the tragic final moments of a UPS cargo plane as it caught fire and crashed in a massive explosion just outside Louisville’s airport, killing at least 12 people and carving a path of destruction on the ground.